Discussion:
In this study the laser
treatments given every six weeks yielded better long-term clinical results
than the treatments given every two weeks. Previous studies [1-5] have
demonstrated good to excellent results for treatment intervals between four
and eight weeks. An earlier study done by the investigators [6] demonstrated
excellent long-term hair reduction using three-week treatment intervals.
Mathematical modeling showed that better laser penetration was achievable at
the hair bulb and bulge in the absence of terminal hair shafts extending to
the skin surface. It was recognized that the success of a hair removal
treatment at a shortened treatment interval was dependent on the regeneration
of melanized target structures for the follow-up treatments [6] The poor
long-term results seen with the shortened treatment interval would suggest
that the laser treatment given only two weeks following the initial treatment
did not yet have an adequate target to absorb the laser's energy. It is
hypothesized that the hair bulb has not yet regenerated at two weeks and hence
the laser treatment was ineffective. The six-week interval allowed adequate
time for the hair bulb and follicle to regenerate therefore providing an
adequate target for the laser and hence, a more effective long-term result.
Conclusions:
The treatment intervals chosen for laser hair removal strongly affect
the efficacy of long-term results. This study demonstrates better efficacy at
the six-week treatment interval compared with the two-week treatment interval.
References:
1. Bjerring P, Cramers M, Egekvist H, Christiansen K, Troilius A.
Hair reduction using a new intense pulsed light irradiator and a normal mode
ruby laser. J Cutan Laser Ther 2000; 2: 63-71.
2. Kauvar AN. Treatment of pseudofolliculitis with a pulsed infrared laser.
Arch Dermatol 2000; 136:1343-6.
3. Eremia S, Li C, Newman N. Laser hair removal with alexandrite versus diode
laser using four treatment sessions: 1-year results. Dermatol Surg 2001; 27:
925-9.
4. Gorgu M, Aslan G, Akoz T, Erdogan B. Comparison of alexandrite laser and
electrolysis for hair removal. Dermatol Surg 2000; 26:37-41.
5. Bencini PL, Luci A, Galimberti M, Ferranti G. Long-term epilation with
long-pulsed neodimium:YAG laser. Dermatol Surg 1999; 25:175-8.
6. Lloyd JR, Mirkov M. Long-term evaluation of the long-pulsed alexandrite
laser for the removal of bikini hair at shortened treatment intervals.
Dermatol Surg 2000; 26:633-7
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